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Depression Case Studies
Patti is a 56-year-old perimenopausal patient with a history of depression. Her depressed mood seems to be responding to her current treatment with the selective
serotonin reuptake inhibitor (SSRI) fluoxetine (40 mg/day); however, she is troubled by hot flashes and night sweats, and she reports some residual depressed mood.
Which treatment strategy is likely to optimize this patient’s chance for remission? (3 points)
How does the recommendation that you just made work? (2 points)
What is the likelihood of achieving remission after the second antidepressant? (2 points)
John is 68 year old who recently suffered a heart attack. He is in cardiac rehab and has become very depressed.
What medication will you consider and why? Is there any antidepressant to avoid? (4 points)
You have started John on an antidepressant, and now he is having sexual side effects.
What would you recommend?
Ray, a 35-year-old male, has only partially responded to his second monotherapy with a first line antidepressant at its maximum dose.
What has the best evidence of efficacy for augmenting an antidepressant in patients with an inadequate response? (4 points)
Donna is a 30-year-old woman who comes to you after being treated with Effexor 75 mg for depression by her PCP for the last 12 months. She reported that her depressive
symptoms have subsided, but she is very anxious.
What would you do? Explain. (2 points)
Jessica just had a baby and cannot remember the name of her antidepressant medication that she was on throughout her pregnancy? She reported that her baby had some
tremors and seemed sluggish, and a little out of it when the baby was in the nursery. They placed the baby in the NICU for some rapid breathing and respiratory
What was wrong? (2 points)
Jessica wants to stay on her antidepressant and continue to breastfeed. What do you think about this? Explain. (4 points)
8. What are the best practices for monitoring and managing conventional and atypical antipsychotics?
7. How are benzodiazepines used as mood stabilizers?
6. What is the relationship between GABA and benzodiazepines? How do benzodiazepines work as anxiolytics?
13. What is the first-line psychotherapy for PTSD?
13. What is 2nd-line psychotherapy treatment for PTSD?