Cancer, Genetics, and Genomics
Rachel comes from a family with a history of breast cancer on her mother’s side. Rachel’s mother died of breast cancer when she was very young. Rachel has two sisters, Lisa and Kristin. Rachel has remained close to Lisa, but she no longer has a relationship with Kristin. At a routine checkup, Rachel is told about the availability of genetic testing for identifying a predisposition to breast cancer. Her doctor recommends the test to Rachel given her family history. Rachel has the genetic testing done and finds that she has a mutated breast cancer 1, early onset (BRCA1) gene. Her doctor tells her she is at high risk for developing breast and ovarian cancer. Rachel’s doctor suggests she ask her sisters to be tested also, so they can take the proper preventative measures. Rachel feels comfortable sharing this information with Lisa, but she has not spoken to Kristin in many years. Rachel tells her doctor that she is not in contact with Kristin and will not make an effort to tell her about BRCA1 and genetic testing. Rachel’s doctor feels confident that she can locate Kristin but worries about breaching patient confidentiality if she goes against Rachel’s wishes.
If you were Rachel’s healthcare provider, what would you do? Provide a rationale for your response. Include the pathological processes associated with breast cancer. What role does the BRCA1 gene contribute to managing the patient’s care? Describe and explain the role of the BRCA1 and breast cancer 2, early onset (BRCA2) gene in contribution as a risk factor for breast cancer. Analyze the risk factors for breast cancer and possible interventions to preventive health management for women and men.
Qatar situated in the western shoreline of the Arabian Gulf. There are around 2.576.181 individuals living in Qatar. When we discuss the territory of Qatar, we should realize that Qatar and all the Arabian Gulf have numerous clans, traditions and conventions. They lived in tents. A standout amongst the most surely understood clans in Qatar is Al-Hajri family. Regardless of All clans in the Middle East had numerous issues in the first yet Al-Hajri family confronted every one of these issues immovably and emphatically. They had the capacity to adapt to the terrible conditions in that time since they were had a place together. There are numerous imperative characters and uncommon conventions in Al-Hajri family, so I will discuss Al-Hajri family and my exploration will feature on their beginnings and customs. Ancestral Nature There are numerous conventions and traditions recognize ancestral individuals as opposed to some other individuals. Ancestral individuals lived just in deserts looking for water and developing creatures, for example, camels and sheep. A large portion of time they set out starting with one place then onto the next. They live in the Middle East particularly in Saudi Arabia, Jordan and Qatar. Around 5 million individuals live in deserts far and wide. They are announcing now. The inborn life is exceptionally troublesome and nobody in some other place can live with them .They have claim way of life and culture. They are glad for their cordiality and liberality. They live in extraordinary tent which made of creatures hair. In their extra time, they typically sing and applaud their hand to their creatures to fulfill them feel. Their sustenance is exceptionally delectable and scrumptious. Their sustenance are rice and flour. They never eat natural products or vegetables. They have exceptional garments. Men dressed just galabia. They additionally cover their head by shalls. They have numerous hues fabrics. Ladies additionally have exceptional dressing. They dressed just Abbaya with brilliantly hues when they went outside. They secured likewise their face and nobody can see them. Innate individuals have numerous dialects and vernaculars recognized them just relying upon their area. History of the clan Al-Hajri Family is a standout amongst the most critical clans in the Middle East, particularly in Qatar. The clan of Al-Hajri originates from the Sharif clan. We realize that Sharif clan emerged from the children of Sharif quality Almzhadji. There are two extraordinary gatherings in Al-Hajri family. The enormous gatherings are Al-Mohammed and Al-almukhddaba. They are viewed as the huge and understood gatherings in the Al-Hajri family. They were situated in the Eastern Province of the territory of Qatar. A large portion of the family clan lived in the southern Saudi Arabia, particularly in the valley of Yaeud and at the base of the valley of Alhvlan. They were lived additionally in the town of Freij in the province of Kuwait and associated with each other. The family was appreciated with the liberality, strength, helping all needy individuals, benevolence and every great deed. There were numerous propensities and conventions recognized them from some other clans in the Middle East. The angling and the pearl driving were the most interests for them.El-Sheik Mohamed Ben Shaban leaded the Al-Hajri family in the start of the thirteen century. He requested them to live in Al-Sarah which situated in the south of Najd. From that point forward, When the Chaffee Ben Safar who is the grandson of the El-Sheik Mohamed Bin Shabban had the title of the pioneer, he exchanged them from the south of Najd to other place. They lived in Hasaa with their pioneer. Some of them additionally passed on and lived in Qatar as of recently. In the Al-Hajri family, there were numerous senior characters, for example, Ibn Shafi, Ibn Ayed and Ibn Baeeth. The Al-Hajri family comprised of seven branches. They were Obeida, Aljuhadr, Sherif, Sanhan, Alhbab, Rafidah, and Bani Bashar. We realize that all clans in the Middle East had numerous traditions and conventions. They voyaged and passed on a considerable measure starting with one place then onto the next place. They voyaged and passed on with a specific end goal to discover water and plants for their sheep and camels, so they called the roaming clan. The highlights and qualities of Al-Hajri family There are numerous highlights and qualities recognized Al-Hajri family. At the point when Al-Hajri family partnered or depended with other family, they submitted by its guarantees and diagrams regardless of whether the endowed to another family prompt slaughtering the last man of their family. There is no said in the history that Al-Hajri family depended to other family and conned it regardless of whether the request came to happening enormous wars. Due to every one of these highlights El-sheik Abdullah Al-Khalifa chose this family and thought of it as a standout amongst the most and solid families among all families in the Middle East and after that El-Sheik Qasem employed them to help him in building up his govern in Qatar. The Al-Hajri family satisfied with all diagrams with El-Sheik Qasem and his administer was set up in this time. El-sheik Fares Nasser Ibn Khalil Al-Shahwan Al-Hajri who was had a place with the Al-Hajri family contributed in building up the run of El-Sheik Qasem. The Co-activity between El-Sheik Qasem and El-Sheik Fares came after Qasem saw that his dad paid much cash which forced to Qatari individuals to the Bahrain ruler under the agreement done in 1968. The base of Al-Hajri family In Al-Hajri family, they separated into numerous branches as takes after: the branch Al-Sultan and they are two sub branches as Al-Khalid including Al-Aswad, Al-Rashdan and Al-Growan. The second sub branch of Al-Sultan is Al-Ghanem including Al-Hotan, Al-Asimy and Al-Samad. There were numerous additionally sub-branches identified with Al-Sultan however they were ceased to exist, for example, Al-Saqr, Al-Safoq and Al-Shreem. The second branch is Al-Fahid and they were six fundamental branches including Al-Doghman, Al-Hobran, Al-Shohiman, AlKober and Al-Goghan. Every one of all these fundamental branches have numerous families. The third branch is Al-Falha and they were recorded under three branches, for example, Al-Baqr including Al-Ramis, Al-Awir and Al-Marbid, the second sub branch of Al-Falha is Al – Shraa including Al-Mohamed and Al-Qrity. The third sub branch is Al-Mosalma among them Al-Nomian and Al-Monqash and there are numerous different families had a place with Al-Falha yet we don’t know anything about them. At last there are numerous different branches, for example, Al-Gadi, Al-Masrir, Al-Zaid and Al-Shhwan. Conclusion There is almost certainly that Qatar is an essential nations on the planet. There are numerous families in the Middle East particularly in Qatar. One of the most grounded and liberality family in Qatar is Al-Hajri family. They situated in many place in various nations like Saudi Arabia, Qatar, Kuwait and Emirates. They are well known by making a trip starting with one place then onto the next place and they not settled on one place. The family have numerous great highlights and attributes like helping individuals and valor. There are numerous things recognized this family, for example, promising and their diagrams with different families. In the history, there is no specified that any one in Al-Hajri family break the religious community with any individual. They helped El-Sheik Qasem to build up his run the show. There are numerous branches in Al-Hajri family like Al-Sultan and Al-Mosalma. At last Al-Hajri family is one of the most grounded and liberality family contrasting with all families in the Middle East.>