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Clinical situation in which you have directly applied evidence-based data

Describe a clinical situation in which you have directly applied evidence-based data to produce a successful patient outcome. If you have not yet done so in practice, describe a clinical situation in which you envision this as a possibility. Explain your process. What steps in the process would you either add or eliminate if you were to encounter this particular set of circumstances again? How could your actions lead to better patient advocacy or a community action? Support your summary and recommendations plan with a minimum of two APRN-approved scholarly resources.

Sample Solution

cological community comprised of commensal, pathogenic and symbiotic microorganisms providing protection against incoming bacterial pathogens. They play a dominant role in modulation of host health by contributing to immunologic, hormonal and metabolic homeostasis. The immune system-microbiota interactions have a symbiotic relationship where microbiota plays an important role in the induction, training, and function of the host immune system and the immune system, in return, maintain these highly diverse and evolving microbes of the host. The immune system is dependent on the microbiota for protection against invading pathogens, but any disturbance in their close relationship can leads to significant risk of microbiota contributing to the disease. From recent studies, we can say that there is sound evidence about microbiota providing protection against viral and autoimmune diseases but also in some diseases they promote the disease progression. Evaluation of complete environment that underlines a disease is extremely important as we move forward in our research and therefore the purpose of this review article is to summarize microbiota’s mechanism in the immune system, evidence of microbiota as immunity booster in different viral diseases, summarizing recent clinical trials of microbiota on different viral diseases and to suggest future directions on research strategies on interaction between immune system and microbiota. Introduction: Multicellular organisms are composed of the macroscopic host and its symbiotic commensal microbiota. These complex communities of microbes include bacteria, fungi, viruses, other microbial & eukaryotic species.1,2 The immune system-microbiota interactions have a symbiotic relationship where microbiota plays an important role in the induction, training, and function of the host immune system and the immune system, in return, maintain these highly diverse and evolving microbes of the host.3 This symbiotic interaction between microbiota and the host helps in functioning of immune system in mammalians, plants, insects and aquatic organisms. Furthermore, the immune system and microbiota also engage “cross-talk” which involves exchange of chemical signals in many animals. This helps immune system to recognize the types of bacteria which are harmful to the host and then combating them, and it also helps in identifying the beneficial microbiota and allowing them to carry out their functions like immune reactivity and targeting.4-5 Mechanisms of microbiota in the immune system: Cytokine induction: Microbiota modulates immune response by acting locally and systemically. Shift in composition and density of microbiota affects systemic immunity. It promotes dermal T cell functio
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