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Living in Italy

Your response should be a maximum of two (2) double-spaced pages. You may choose any person you have
known personally or any place that was important in your life as your topic. FOR MY TOPIC: When I
lived in Italy for a year and how wonderful of an experience it was. I moved there from the USA and back to the
USA now.
* However, you must demonstrate mastery of the following in your paragraph. Therefore, the
depth (length) of your paragraph must be sufficient to demonstrate these concepts.
a. Topic Sentence – Be sure this is a general statement that states the person, place, or thing you will describe.
Highlight this sentence in aqua blue. (10 points)
b. Body Sentences – Be sure to select ideas and write sentences that appeal to the senses (sight, sound,
smell, taste, and/or touch) and that are definitely related to the topic sentence. The quality and relationship of
these sentences will be evaluated. (10 points)
c. Coherence: Be sure that you organize your paragraph in the best way possible. A coherent paragraph is
clear, logical, and readable.
(1) Order: Select the best order for your paragraph (time, space, or importance). Select transitions for your
paragraph that demonstrate your understanding of the order. At a minimum, you must use three (3) transitions
to demonstrate your understanding of this concept. Highlight these transitions in yellow. (15 points)
(2) Related Sentences: Be sure to repeat words and ideas; use synonyms and substitutions to demonstrate
your understanding of this concept. Highlight these related words or sentence parts in gray. (15 points)
d. Sentence Structure: In your paragraph, demonstrate your understanding of the following sentence
structures. You must demonstrate at least one (1) of EACH of the following structures. Highlight these in green.
(5 points each, for a possible total of 20 points)
(1) Coordinating conjunction
(2) Semicolon
(3) Conjunctive adverb
(4) Subordinate clause followed by an independent clause
e. Concluding Sentence: Be sure to complete your paragraph with a well-written concluding sentence. (15
f. Mechanics and Grammar – Be sure that you complete the final step of the writing process: proofreading.
Your paragraph should be free from sentence construction errors and should be spell-checked. (15 points)

Sample Solution

The advantages of pH-sensitive nanoparticles over other nanoparticles include: (a) the majority of carriers have been used as enteric-coating materials for a long time, and their safety has been approved. (b) The carriers show rapid drug release and then high drug concentration gradient as they undergo quick dissolving at definite pH and definite sites. The phenomenon is beneficial for the drug absorption. (c) They improve drug absorption comparing to the other conventional nanoparticles as they turn from the solid state to the hydrogel state at certain dissolution pH and so, the bioadhesion of the carrier to the mucosa becomes greater at specific fragment. (d) The drug stability can be enhanced more effectively using pH sensitive nanoparticles. Different materials can be used for preparation of pH-sensitive nanoparticles: a- pH-sensitive nanoparticles prepared from polyanions: Such as Eudragits and HPMC phthalate. b- pH-sensitive nanoparticles prepared from publications: Chitosan is the main cationic polymer used to prepare pH-sensitive nanoparticles. It is the second most plentiful polymer in nature after cellulose. c- pH-sensitive nanoparticles prepared from the mixture of polyanions and polycations: Some techniques have been improved using the advantages of both polyanions and polycations [97,108, 113-116]. Most of the nanoparticle systems related consist of the positive-charged chitosan and a negative-charged polymer, such as Eudragit [97, 115, 117], poly (g-glutamic acid) [113, 114, 116]

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