Pay for Performance Controversial

Posted on April 28, 2022 | by Belinder

Write a 4-page research paper, titled Pay for Performance Controversial in APA 7 format using the terms, concepts, and theories in the chapters provided on the main points below (they become Level One Headings).

Choose any U.S. based business entity and answer the 3 points below:

Identify how an organization could measure the effectiveness of their pay-for-performance plans (provide examples to support your ideas or concepts).
Discuss the disadvantages of using a pay-for-performance plan from an employee’s perspective.
Discuss the disadvantages of using a pay-for-performance plan from an employer’s perspective.

Sample Solution

A strain of E.coli has been isolated that can’t correct any replication errors. It has a mutated ε subunit so that Pol III HE can still function as a polymerase but has lost its proofreading function as a 3’ to 5’ exonuclease. This E.coli strain also has a non-functioning mismatch repair system. By considering the replication error rates in a wild type strain and the mutant strain, discuss the consequences of these mutations on the E. coli genome. To help with your discussion, think about the following questions: • What is the normal replication error rate in E. coli? • If you find an article that says something like an error rate is 5 x 10-2 errors per base pair, this means that 5 nucleotides every 100 base pairs is mutated. • What is the base selection error rate of DNA pol III? That is, what is it’s rate of error when choosing which nucleotide to insert during DNA synthesis of replication? • What is the genome size of E. coli? • How many mutations would there be each generation of each E.coli strain? • How many replications would it take for every nucleotide within the genome of the mutant strain to become mutated? • Discuss the consequences of these mutations on the E. coli genome.

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