Reflect on how these genetics and age might impact decisions related to preventive services. • Describe available preventive services that providers might recommend for patients at risk of the type of cancer you selected. • Explain how the factors you selected might impact decisions related to preventive services. • Describe drug treatment options for patients diagnosed with the type of cancer you selected. Explain the short-term and long-term implications of these treatments. Regerences 1) Hopper, J. L., Dite, G. S., Maclnnis, R. J., Liao, Y., Zeinomar, N., Knight, J. A., … kConFab Investigators. (n.d.). Age-specific breast cancer risk by body mass index and familial risk: prospective family study cohort (ProF-SC). BREAST CANCER RESEARCH, 20. https://doi-org.ezp.waldenulibrary.org/10.1186/s13058-018-1056-1
2)http://www.ahrq.gov/professionals/clinicians-providers/guidelines-recommendations/guide/section2.html: BRCA-Related Cancer In Women Title Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer In Women Population Asymptomatic women who have not been diagnosed with BRCA-related cancer Recommendation Screen women whose family history may be associated with an increased risk for potentially harmful BRCA mutations. Women with positive screening results should receive genetic counseling and, if indicated after counseling, BRCA testing. Grade: B Do not routinely recommend genetic counseling or BRCA testing to women whose family history is not associated with an increased risk for potentially harmful BRCA mutations. Grade: D Risk Assessment Family history factors associated with increased likelihood of potentially harmful BRCA mutations include breast cancer diagnosis before age 50 years, bilateral breast cancer, family history of breast and ovarian cancer, presence of breast cancer in male family member, multiple cases of breast cancer in the family, ?1 or more family member with 2 primary types of BRCA-related cancer, and Ashkenazi Jewish ethnicity. Several familial risk stratification tools are available to determine the need for in-depth genetic counseling, such as the Ontario Family History Assessment Tool, Manchester Scoring System, Referral Screening Tool, Pedigree Assessment Tool, and FHS-7.
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