- Is cocaine found in a plant or is it synthesized in a lab?
• Cocaine is a naturally occurring molecule from the Coca plant - What is the difference between crack cocaine and freebase cocaine in terms of the how the two drugs are made (just the basics here…)?
- How was cocaine used in the late 1800s and early 1900s?
• Was used in coca cola as a stimulant, as a local anesthetic (in dental procedures) - What effect does cocaine have on blood vessels?
• Cocaine tends to constrict blood vessels speeding up blood flow but paradoxically decreasing Cocaine absorption - How is cocaine metabolized and what is the metabolite? How is cocaethylene formed?
• Benzoylecgonine is the metabolite of Cocaine. Cocaethylene is formed by mixing alcohol and cocaine when they are both being processed in the body. It
also makes it more addictive
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