Factsheet - Inflammation & Vitamin D

  Description:   Using a maximum of 1 x AA page (front and back) and no more than 1000 words is to prepare a ‘FACT SHEET’ which reviews the evidence linking obesity with systemic inflammation and the potential treatment of this inflammation with vitamin D- You fact sheet is aimed at a busy healthcare professional and so it needs to be both factual and succinct- Pictue a GP sitting down at their desk to eat a 15 min lunch between patients - and they pick up you factsheet... The factsheet can be divided into two parts: Part 1: Review and describe the link between obesity and inflammation- The basis of this link is discussed within the first lectue and associated resouces- Within part 1 you are also asked to briefly review the following biomarkers: o Macrophages (focus on macrophage infiltration into obese adipose tissue) 0 TNF alpha 0 Nitric oxide production 0 T cell function These can be listed and described using a table format- Part 2: Provide evidence on the effectiveness of treating inflammation with vitamin D Following a review of the literatue you are asked provide evidence as to whether increasing vitamin D levels in an obese person might improve the functioning of the biomarkers described in part 1- The improvement may be the result of a variety of factors including weight loss- You are also asked to provide 3 tips/hints as to how vitamin D might be increased by an obese person- You can certainly refer to peak health bodies such as NSA, heart foundation or the Department of Health- Make you recommendations achievable and safe for the individual-.1he aim is to help the health professional help their patients and so the suggestions need to be “real”-