Heath Professional Essentials

Diabetes mellitus is a major world health problem. Treatment and management of diabetics is a very significant issue for governments, society and both pharmacists and pharmaceutical companies. Completin" rel="nofollow">ing this assignment will help you to gain" rel="nofollow">in a deeper understandin" rel="nofollow">ing of diabetes mellitus. The length of this assignment excludin" rel="nofollow">ing graphs, figure legends and references should be no more than 1000 words. The % of marks allocated to each section is a guide to the word length for that section. Where appropriate references should be in" rel="nofollow">included usin" rel="nofollow">ing the Harvard System cited appropriately in" rel="nofollow">in the text with correct formattin" rel="nofollow">ing in" rel="nofollow">in the reference list. As a guide a min" rel="nofollow">inimum of 4 but no more than about 12 references should be used. You are advised to use references from both primary and secondary sources. Assignments should be typed and submitted usin" rel="nofollow">ing learnonlin" rel="nofollow">ine via the Course Website. Graphs must be thoughtfully in" rel="nofollow">incorporated in" rel="nofollow">into the text. Due date/time is 11.00PM June 7 th . 1. Why is the disease given the name diabetes mellitus? How does diabetes mellitus differ from diabetes in" rel="nofollow">insipidus? (5% of assignment marks) 2. Individuals with the diabetes mellitus are classified in" rel="nofollow">into two main" rel="nofollow">in groups. What are they and what is the basis of the classification system used? (5% of assignment marks) 3. How are patients diagnosed as diabetics? What treatment options are most used to manage this condition? (20% of assignment marks) 4. What changes in" rel="nofollow">in the metabolism of glucose and fat (triglycerides) are observed in" rel="nofollow">in this disease? What symptoms might a diabetic show as a result of these metabolic changes and why do these occur? (40% of assignment marks) 5. Two overnight fastin" rel="nofollow">ing patients, A & B, were each given a dose of 75g of glucose at time zero. Their blood glucose levels were measured at 0, 30, 60, 90, 120 and 240 min" rel="nofollow">inutes after in" rel="nofollow">ingestion of the glucose usin" rel="nofollow">ing a glucose specific assay. The brief procedure for this assay is:- a. Add 5.0 ml of assay reagent to sufficient tubes for the assay b. Add 0. 1 ml of each glucose standard to a tube of assay reagent c. Add 0. 1 ml of each test serum to a tube of assay reagent. d. Mix the contents of each tube and read the absorbance at 625 nm. The results obtain" rel="nofollow">ined are shown in" rel="nofollow">in the two tables below. Table 1 - standards Glucose standard (mmol/L) Absorbance @ 625 nm 0 0.02 3 0.21 6 0.43 9 0.65 12 0.83 Table 2 – patient results Time (min" rel="nofollow">in) Absorbance-Patient A Absorbance-Patient B 0 0.26 0.47 30 0.51 0.63 60 0.25 0.80 90 0.23 0.76 120 0.24 0.63 240 0.30 0.58 Plot a standard graph of absorbance at 625 nm again" rel="nofollow">inst glucose concentration You must use Excel. Determin" rel="nofollow">ine the concentration of glucose in" rel="nofollow">in each patient serum sample and plot glucose concentration again" rel="nofollow">inst the time over which the samples were obtain" rel="nofollow">ined. Comment on the results for the two patients (15% of assignment marks) 6. What potential long term problems would a pharmacist need to be aware of when advisin" rel="nofollow">ing a diabetic client?