Heparin and Anticoagulants

Heparin" rel="nofollow">in and Anticoagulants Paper details: lT SHOULD BE 650-WORDS PAPER Unfractionated heparin" rel="nofollow">in (UP) is sometimes used. How would in" rel="nofollow">initial therapy with heparin" rel="nofollow">in be started and doses adjusted. To that same end, one must also consider monitorin" rel="nofollow">ing of therapy. Heparin" rel="nofollow">in Dosin" rel="nofollow">ing: Weight-Based Nomogram (8ou/kg bolus and 18u/kg/h) in" rel="nofollow">initially followed by: aPTT (sec) Dose Change in" rel="nofollow">in units/kg/hr Additional Action Next aPTT (hr) <35 (<1.2x mean normal)+4 Rebolus with 8ounits/kg 6 35-45 (1 .2-1 .5X mean normal) +2 Rebolus with 4ounits/kg 6 46-70 (1 .5-2.3X mean normal) 0 0 6 (once daily after 1$t 24h) 71-90 (2.3-3x mean normal) -2 0 6 >90 (>3x mean normal) -3 Hold in" rel="nofollow">infusion 1 hours What is the next aPTT check accordin" rel="nofollow">ing to the nomogram always 6 hours after a start or change how should you in" rel="nofollow">interpret an aPTT of 36 seconds at 6 hours after the last change and what should your plan of action be? how should you in" rel="nofollow">interpret an aPTT of 42 seconds at 2 hours after the last change and what should your plan of action be? How Does the use of LMWH compare to that of UF? Conditioner especially monitorin" rel="nofollow">ing, ease of use, etc Next, consider NOACs. What agents are available for DVT and are there advantages / disadvantages compared to: UF followed by warfarin" rel="nofollow">in LMWH followed by warfarin" rel="nofollow">in Fondaparin" rel="nofollow">inux followed by warfarin" rel="nofollow">in How should therapy with warfarin" rel="nofollow">in be in" rel="nofollow">initiated and monitored If dosage adjustments are necessary, how should they be made? HOW ShOUld elevated lNRS be handled? Why can't warfarin" rel="nofollow">in be used as in" rel="nofollow">initial therapy (monotherapy) for DVT? Can NOACs be used as monotherapy? What if our patient is pregnant? . Chat With "5