• SARS-CoV2 viral particles entered Jean’s nasal cavity and attached to the respiratory mucous membranes.
• Some mucosal barriers prevent part of the viral particles to penetrate the respiratory epithelium. Which are
these barriers and how do they act?
• Which cells are recruited from the bloodstream to the connective tissue (under the respiratory epithelium) to
phagocyte the viral particles? Explain the recruitment mechanism.
• After a few days of the infection, Jean’s adaptive immune system is ready to attack the remaining viral
particles that were not efficiently destroyed by the innate immunity army.
• Explain one mechanism of antibody action against viruses.
• Is it possible for the immune system to eliminate the viruses without B cells? Why or why not? (This question
will be graded based on your ability to think critically – even if the event described is not realistic.)
• The T cell response follows the antibody-mediated B cell immunity.
• What is the connection between B and T cells to build an effective immune response to SARS-Cov2?
• Is it possible for the immune system to eliminate the viruses without T cells? Why or why not?
Sample Solution