Question 1: (~2 pages) Ebola is a virus of zoonotic origin that can cause epidemics among human populations as in the West African epidemic in 2014-15. What level of control is achievable against Ebola? Is Ebola ultimately eliminable or eradicable and what would it take to achieve this state, assuming a highly effective vaccination program is unattainable? Reflect on other systems such as smallpox, polio, and measles etc. in support of your arguments.
Two Ebola vaccines have been approved (please see the following two links):
Question 2: (~2 pages) Currently approved COVID vaccines are of mixed efficacy and limited availability. What would be the role of surveillance in curtailing transmission and monitoring viral variants? How would you design this system? Discuss symptomatic case detection versus asymptomatic community testing and pathogen (antigen) detection versus antibody testing.
Sample Solution