Construct a paragraph describing the interrelationship among the microbial pathogen, the affected host, and
potential antimicrobial drugs in the development of appropriate chemotherapeutic treatment.
A critically ill patient enters your emergency room, exhibiting signs and symptoms of severe septic shock. In
this case, should you immediately begin treatment with a broad-spectrum drug or a narrow-spectrum drug?
Explain your answer and discuss any possible consequences of using either drug in the patient.
Amphotericin B is often referred to as “Amphi-Terrible” in medical settings due to its effects on treated patients.
Describe when this drug should be prescribed, and provide a biological reason for its damaging activity on host
cells. HAART, or highly active antiretroviral therapy, is currently recommended for the treatment of HIV and
involves the administration of three or more medicines at one time. Explain why this combined therapy
approach is more effective than single-drug treatment in the management of HIV infection, providing current
evidence to support your answer.
Sample Solution