Literary Article Critique

ANGPTL4 variants and their haplotype are associated with serum lipid levels the risk of coronary artery disease and ischemic stroke and Atorvastin cholesterol lowering responses. Authors: Qian Yang 1,Rui-xinglYinl,Xiao -Li Cao2, Feng Huang 1,Yi-Jiang Zhouland Wu-Xian Chen1 Yang et al. Nutrition and Metabolism https://doi.org/10.1186/s12986-018-0308-5 My PICOT QUESTION must be included in the the beginning of the assignment. What is the effects of daily aspirin regimen versus aspirin with a Statin in reducing recurring strokes in six months? Please answer the following questions: 1. Was the literature review up to date,explain your answer? 2. Did the review provide a state of the art synthesis of evidence on the problem? 3. Did the review point out the gaps in the research providing a strong basis for the new study? 4. Did the study reference a theoretical framework or conceptual model? What was it? Do you think it was appropriate and why? 5. Were research concepts and variables clearly defined? Provide a brief description of each      

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