The first part of the poster project is to create an over view of carbohydrate metabolism, citrate cycle, and oxidative phosphorylation. We will use the liver cell as a prototype, and we assume it can carry out almost every reaction. There are exceptions of course, animals don't have the enzymes to carry out carbon fixation.
To start, draw a large cell (which has a phospholipid bilayer), and include a mitochondrium. You will need endoplasmic reticulum as well, since one reaction of gluconeogenesis happens there. Mitochondria have a double membrane, the outer membrane is permeable but and the inner membrane is not, so you will need to include transporter proteins.
Draw the pathways into the correct compartment, including structures and enzymes, and make connections with metabolites in the other compartments. Make sure not to duplicate pathways inside the same compartment, goal is to integrate the metabolic routes.
We will work with groups of 4, only 1 submission per group. Due on February 25.
Routes to be included: (but you only need to do number 3)
glycolysis/gluconeogenesis
glycogen synthesis/breakdown
pentose phosphate pathway
citrate cycle
oxidate phosphorylation
It is better not to cut and paste structures from internet, instead draw the structures and pathways by hand or on iPad/tablet with a stylus.
Sample Solution