Pharmacology

Dipeptidyl Peptidase 4 inhibitors, Long Acting Insulin, and glucagon
a. Summary of Diabetes mellitus drug class

b. Assigned group drug classification

c. List of common medications under the class-generic and trade names

Select a prototype drug of the classification and discuss:

Indication or Therapeutic action for disease states
Mechanism of Action
Pharmacokinetics: ADME (Absorption, Distribution, Metabolism & Excretion)
Available forms, dosage ranges and factors that shape dosage ranges
Contraindications/Precautions/Interactions
Side/Adverse Effects: Preferably by systems noting most frequent and life-threatening effects
Nursing interventions and client teaching including Point of Care Test (POCT) value range for hyperglycemia and hypoglycemia, hypoglycemic management for conscious and unconscious patients (see posted algorithm), use of sliding scale, onset, peak, and duration of assigned insulin
Evaluation: What determines the effectiveness of the drug therapy (minimum of 3 factors)

Sample Solution