prostate cancer

prostate cancer Order Description it is a Biology and Laboratory Investigation of Disease. Structure: Introduction: (600 words) Patient’s history and symptoms Mutation in the gene CHEK2 reflecting prostate cancer (The patient has a Single Nucleotide Polymorphism in his genome with access code on NCBI Gene Bank dbSNP rs121908702 Please comment on this mutation in your case study report. Prostate cancer (brief background) Thesis statement of the conducted tests. Discussion: (2000 words) Analysis of laboratory findings. Discussion of the significance of the full range of results. Do not include the table… use it in written words. Urea    18 mmol    Ref(3.6 – 7.1 mmol)    abnormal Creatinine clearance    79.35 ml/min    Ref (70-75 ml/min)    abnormal Alkalinephosphate    112 IU/L    Ref(30-90 IU/L)    abnormal Bilirubin    96.9 umol/L    Ref( up to 20)    abnormal Bacteria Culture    •    Bacterial identification using Gram stain, different biochemical tests and antibiotic disk gives an evidence of P.mirabilis presence Histology    Haematoxylin and Eosin section obtained by Fine Needle Biopsy. Histologically we belive that it is an Intraductal carcinoma: solid growth of malignant cells with marked nuclear atypia- Peripheral Blood Film    red cell rouleaux,possible moderate leukocytosis but clearly features of leukoerythroblastic features-namely myelocytes, promyleocytes and occasional blast cells. I did not see any but I also beleive there are nucleated Red Blood Cells present but in small numbers. There is no eidence of pronounced thrombocytopaenia. PSA    55 ng/ml    Ref( below 4.0 ng/ml)    abnormal PT    Patient(45 second)    Control (45 second)    Abnormal PTT    Pstient(120 second)    Control ( 35 second)    abnormal Thrombin time    Patient( 50 second)    Control (15 second)    abnormal Explaining the pathophysiology that resulted from the prostate cancer that have led to for the abnormal result, for example (use as a hints): •    enlargement of the prostate caused urethra obstruction that have created an environment for the bacteria (P.mirabilis) that might have caused the stones by releasing an enzyme called urease that breakdown the urea which result in a residue that form the stone in the kidney. •    Rising of Creatinine clearance could indicate stage 3 moderately decreased GFR or kidney failure (how that links with result and prostate cancer and urine retention) •    ALK rise could indicate cancer metastasis. •    Disseminated intravascular coagulation in relation to prostatic carcinoma. •    Each result should be explained in the relation to the prostate cancer. Conclusion (400 words): •    A sum up for the case. •    Treatment •    Further possible laboratory test that will help in the identification ( please note do not mention other medical tests such as CT,MRI ..etc) Please try to link symptoms, signs and laboratory tests result with the case in front of you and note that the range of lab tests we had is not sufficient to make a definitive decision so we might need to ask for further test. Report The case study report should contain the following;- •    Details of case study i.e. clinical history. •    An outline of the laboratory investigation. •    Analysis of laboratory findings. •    Discussion of the significance of the full range of results. •    Suggestions for additional (confirmatory) tests •    Conclusions •    Appendix: sample details and method sheets.        PLACE THIS ORDER OR A SIMILAR ORDER WITH US TODAY AND GET AN AMAZING DISCOUNT :)