The Tuskegee Syphilis Experiment.

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Epidemiology relies on various observational study designs to investigate disease occurrence and associated factors. These designs differ in their approach, scope, strengths, and limitations. Understanding these differences is crucial for interpreting research findings and building a comprehensive picture of public health issues (Celentano & Szklo, 2019). We will examine one example each of a case report, case series, and cross-sectional study.

1. Case Report

  • Definition: A case report provides a detailed account of a single patient, often focusing on unusual or novel occurrences. This could include unexpected symptoms, a rare disease presentation, an unforeseen adverse reaction to treatment, or a unique therapeutic outcome (Aschengrau & Seage, 2020). Case reports are valuable for generating hypotheses, identifying new health problems, and sharing unique clinical experiences, but they cannot establish causality or be generalized due to their focus on just one individual.

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