Cystic fibrosis

Cystic fibrosis is a genetic disorder caused by a defective membrane transport protein. The defective protein closes chloride channels in membranes, preventing chloride from being exported out of cells. This results in the development of thick mucus on the outer surfaces of cells. This mucus clogs the ducts that carry digestive enzymes from the pancreas to the small intestine, clogs the airways to the lungs, and promotes lung infections. Why do you think the defective protein results in a thick, sticky mucus outside the cells, instead of loose, fluid covering?

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